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KMID : 1144320220540030553
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감염과 화학요법
2022 Volume.54 No. 3 p.553 ~ p.558
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A Transient Effect of Convalescent Plasma Therapy in a Patient with Severe Covonavirus Disease 2019: A Case Report
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Baek Ae-Rin
Choo Eun-Ju
Kim Ji-Yeon
Ha Tae-Sun
Park Sung-Woo
Shin Hee-Bong
Park Seong-Kyu
Park Joo-Hyun
Kim Tark
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Abstract
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A 65-year-old male patient with an end-stage renal disease was diagnosed with coronavirus disease 2019 (COVID-19) by reverse transcription polymerase chain reaction. The patient complained of cough, sputum, and respiratory distress that worsened three days ago. The patient required mechanical ventilation and extracorporeal mentrane oxygenation. On day 9, convalescent plasma collected from a 34-year old man who recovered from COVID-19 45 days ago was administered. The patient showed immediate clinical improvement. However, on day 14, the patient’s clinical course worsened again. On day 19 and day 24, vancomycin-resistant Enterococcus faecium bacteremia and methicillin-resistant Staphylococcus aureus pneumonia were found. After long-term supportive care, he slowly recovered. He was discharged on day 91 without any oxygen requirement. This case report suggests that convalescent plasma therapy might just provide a short-term relief and that persistent effort for critical care is necessary to save patients from severe COVID-19.
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KEYWORD
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Convalescent plasma, Coronavirus disease 2019, Therapy
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